Epidermolysis Bullosa (EB)

Epidermolysis Bullosa (EB) is defined as an inherited genetic skin condition in which the skin blisters easily. This could be from anything ranging from a scratch, heat, a minor injury, or anything else that could cause irritation to the skin. This disease can also affect the inside of the body, including blistering of the lining of the mouth and stomach. According to MedlinePlus, a government organization that provides up-to-date medical information, one in 30,000 to 50,000 people suffer from Epidermolysis Bullosa (EB) (“Epidermolysis Bullosa Simplex”). This rare disease varies in severity, with the mildest being Epidermolysis Bullosa simplex. This type of EB usually only occurs in specific areas of the body including the hands and feet. In contrast, the most severe type of EB is the Dowling-Meara type, in which blistering can spread anywhere on the body, including the inside of the mouth. Patients of the Dowling-Meara type can experience an overproduction of keratin in their nails, feet, or palms, causing a thick layer of skin to form, also known as hyperkeratosis (“Epidermolysis”). This condition does not often occur in children; rather, it usually occurs in young adults. Symptoms include overly sensitive skin, milia, scarring alopecia, blistering in the throat or mouth, tooth decay, etc. People who experience these symptoms are recommended to visit a dermatologist to receive a proper diagnosis and treatment.

Although there is no cure for this disease, there are some common treatments that work to alleviate pain and decrease risk factors. According to the National Health Service in England, treatments include removing occuring blisters using a sterile needle, applying protective wear that prevents further blistering, and overall avoiding things that could increase the risk of scarring and blistering (“Overview”). Despite the fact that EB is extremely rare, it is still important to spread awareness of this condition as it may be proven useful in future scenarios. People who suffer from this condition may feel anxious and overwhelmed as it is a harrowing experience in which the rest of the world is unaware of. Research about this condition is still being done, so raising awareness would help to show people who have been diagnosed not just with EB but any other rare condition that they are not alone in their experience.

References

“Epidermolysis Bullosa Simplex.” MedlinePlus. 1 Jul. 2020. medlineplus.gov/genetics/condition/epidermolysis-bullosa-simplex/#:~:text=Epidermolysis%20bullosa%20simplex%20is%20one,such%20as%20rubbing%20or%20scratching. Accessed 20 Nov. 2022.

“Overview: Epidermolysis Bullosa.” National Health Service UK. 23. Jun. 2021, www.nhs.uk/conditions/epidermolysis-bullosa/. Accessed 20 Nov. 2022.